Title : Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor.

Pub. Date : 2005 Jul

PMID : 15802384






1 Functional Relationships(s)
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Protein Name
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1 Phenobarbital-like inducer, 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is a potent mouse CAR ligand that has been used to study CAR target genes in mice but does not activate human CAR (hCAR) or rat CAR (rCAR). 1,4-bis(2-(3,5-dichloropyridyloxy))benzene nuclear receptor subfamily 1, group I, member 3 Rattus norvegicus