Title : Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes.

Pub. Date : 2005 May 6

PMID : 15796891






3 Functional Relationships(s)
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Protein Name
Organism
1 Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes. Glyceraldehyde vascular endothelial growth factor A Homo sapiens
2 While no type of AGE we examined changed the permeability of endothelial sheets, glyceraldehyde-derived AGE induced VEGF expression most significantly in astrocytes. Glyceraldehyde vascular endothelial growth factor A Homo sapiens
3 These results indicate that glyceraldehyde-derived AGE is the biologically active substance for astrocytes by regulating the VEGF and GDNF expression, which is causally contributing to an increase in the permeability of the BBB. Glyceraldehyde vascular endothelial growth factor A Homo sapiens