Pub. Date : 2005 May 6
PMID : 15796891
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes. | Glyceraldehyde | vascular endothelial growth factor A | Homo sapiens |
2 | While no type of AGE we examined changed the permeability of endothelial sheets, glyceraldehyde-derived AGE induced VEGF expression most significantly in astrocytes. | Glyceraldehyde | vascular endothelial growth factor A | Homo sapiens |
3 | These results indicate that glyceraldehyde-derived AGE is the biologically active substance for astrocytes by regulating the VEGF and GDNF expression, which is causally contributing to an increase in the permeability of the BBB. | Glyceraldehyde | vascular endothelial growth factor A | Homo sapiens |