Title : Cholinesterase inhibitory and spasmolytic potential of steroidal alkaloids.

Pub. Date : 2004 Dec

PMID : 15795993






1 Functional Relationships(s)
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1 Structure-activity relationship suggested that the nitrogen substituents at C-3 and/or C-20 of steroidal skeleton and the hydrophobic properties of the pregnane skeleton are the key structural features contributed to the inhibitory potency of these steroidal alkaloids against AChE and BChE. Pregnanes cholinesterase Oryctolagus cuniculus