Title : Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.

Pub. Date : 2005 Oct 1

PMID : 15790787






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1 Taken altogether, our data demonstrate that IFNs and imatinib mesylate differentially regulate PI 3" kinase/mTOR-dependent signaling cascades in BCR-ABL-transformed cells, consistent with distinct effects of these agents on pathways regulating mRNA translation. Imatinib Mesylate peptidase inhibitor 3 Homo sapiens