Pub. Date : 2005 Apr
PMID : 15790450
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The objective of this study was to determine if p53 is involved in the mechanism of RA radiosensitization. | Tretinoin | tumor protein p53 | Homo sapiens |
| 2 | RESULTS: RA (5 microM 9-cis-RA) radiosensitized the SiHa and CC-1 cell lines that contain HPV-degraded p53, but did not radiosensitize the SW962 cell line, which is HPV negative and contains wild-type p53, nor the C33a cell line, which contains mutant p53 (R273C). | Tretinoin | tumor protein p53 | Homo sapiens |
| 3 | RESULTS: RA (5 microM 9-cis-RA) radiosensitized the SiHa and CC-1 cell lines that contain HPV-degraded p53, but did not radiosensitize the SW962 cell line, which is HPV negative and contains wild-type p53, nor the C33a cell line, which contains mutant p53 (R273C). | Tretinoin | tumor protein p53 | Homo sapiens |
| 4 | RESULTS: RA (5 microM 9-cis-RA) radiosensitized the SiHa and CC-1 cell lines that contain HPV-degraded p53, but did not radiosensitize the SW962 cell line, which is HPV negative and contains wild-type p53, nor the C33a cell line, which contains mutant p53 (R273C). | Tretinoin | tumor protein p53 | Homo sapiens |