Title : The antifolate activity of tea catechins.

Pub. Date : 2005 Mar 15

PMID : 15781612






1 Functional Relationships(s)
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Protein Name
Organism
1 EGCG exhibited kinetics characteristic of a slow, tight-binding inhibitor of 7,8-dihydrofolate reduction with bovine liver DHFR (K(I) = 0.109 micromol/L), but of a classic, reversible, competitive inhibitor with chicken liver DHFR (K(I) = 10.3 micromol/L). epigallocatechin gallate dihydrofolate reductase Bos taurus