Pub. Date : 2005 Jan-Mar
PMID : 15780031
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Supplementation with either inositol or IP6, or their combination, starting one week prior to administration of DEN, resulted in a significant decrease in both the area and the number of placental glutathione S-transferase positive (GST-P+) foci, a preneoplastic marker for DEN-initiated hepatocarcinogenesis. | Phytic Acid | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 2 | Supplementation with either inositol or IP6, or their combination, starting one week prior to administration of DEN, resulted in a significant decrease in both the area and the number of placental glutathione S-transferase positive (GST-P+) foci, a preneoplastic marker for DEN-initiated hepatocarcinogenesis. | Phytic Acid | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 3 | The administration of inositol and/or IP6 in drinking water caused marked enhancement in the glutathione S-transferase (GST) activity. | Phytic Acid | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 4 | The administration of inositol and/or IP6 in drinking water caused marked enhancement in the glutathione S-transferase (GST) activity. | Phytic Acid | hematopoietic prostaglandin D synthase | Rattus norvegicus |
| 5 | Based on these findings, it is likely that the chemopreventive effects of inositol and/or IP6 on rat hepatocarcinogenesis initiated by DEN and promoted by PH are associated with induction of GST activity and suppression of lipid peroxidation. | Phytic Acid | hematopoietic prostaglandin D synthase | Rattus norvegicus |