Title : Stat3 activity in melanoma cells affects migration of immune effector cells and nitric oxide-mediated antitumor effects.

Pub. Date : 2005 Apr 1

PMID : 15778348






1 Functional Relationships(s)
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1 TNF-alpha and IFN-beta, which are secreted by Stat3-inhibited tumor cells, are able to activate macrophage NO production, whereas neutralizing TNF-alpha in the tumor supernatant from Stat3-blocked tumor cells abrogates nitrite production. Nitrites interferon beta 1, fibroblast Mus musculus