Title : Signaling mechanism for the insulin-like effects of growth hormone--another example of a classical hormonal negative feedback loop.

Pub. Date : 2005 Mar

PMID : 15777207






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Downstream PI3-kinase protein kinase B/Akt participates in the activation of glucose transporters (GLUT4) and increased glucose uptake as well as activation of phosphodiesterase 3B and hydrolysis of cAMP leading to a net dephosphorylation of the hormone sensitive lipase and inhibition of lipolysis. Cyclic AMP AKT serine/threonine kinase 1 Homo sapiens