Title : Patupilone acts as radiosensitizing agent in multidrug-resistant cancer cells in vitro and in vivo.

Pub. Date : 2005 Feb 15

PMID : 15746064






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1 Here we have investigated the effect of combined treatment with ionizing radiation and patupilone or paclitaxel in the P-glycoprotein-overexpressing, p53-mutated human colon adenocarcinoma cell line SW480 and in murine, genetically defined E1A/ras-transformed paclitaxel-sensitive embryo fibroblasts. epothilone B tumor protein p53 Homo sapiens