Title : Promoter hypermethylation of mismatch repair gene hMLH1 predicts the clinical response of malignant astrocytomas to nitrosourea.

Pub. Date : 2005 Feb 15

PMID : 15746058






1 Functional Relationships(s)
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1 CONCLUSIONS: The present study identified hMLH1 methylation status as a predictor of the clinical response of malignant astrocytomas to chloroethylnitrosourea-based adjuvant therapy. 1-(2-chloroethyl)-1-nitrosourea mutL homolog 1 Homo sapiens