Title : Variable regions 1 and 2 (VR1 and VR2) in JSRV gag are not responsible for the endogenous JSRV particle release defect.

Pub. Date : 2005 Jan

PMID : 15744563






2 Functional Relationships(s)
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1 We previously localized a particle release defect of the full-length endogenous-derived expression construct pCMV2enJS56A1 to the amino-terminal region of gag that incorporates the two variable regions VR1 and VR2, which harbor the main sequence differences between endogenous and exogenous JSRV in this part of gag. Glycosaminoglycans vault RNA 1-2 Homo sapiens
2 These results point to a small number of amino acids lying outside of VR1 and VR2 that may be responsible for the particle defect of enJS56A1 Gag. Glycosaminoglycans vault RNA 1-2 Homo sapiens