Title : The macrophage alphaMbeta2 integrin alphaM lectin domain mediates the phagocytosis of chilled platelets.

Pub. Date : 2005 May 6

PMID : 15741160






2 Functional Relationships(s)
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1 alpha(M)beta(2) also recognizes beta-GlcNAc residues on GPIbalpha that are clustered on platelets after cooling. Acetylglucosamine glycoprotein Ib platelet subunit alpha Homo sapiens
2 Therefore chilled platelets are removed from blood by an interaction between beta-GlcNAc residues on clustered GPIbalpha and the lectin domain of alpha(M) chain of the alpha(M)beta(2) integrin, distinguishing this interaction from those mediated by the alpha(M) I domain. Acetylglucosamine glycoprotein Ib platelet subunit alpha Homo sapiens