Title : Up-regulation of vascular endothelial growth factor-C by nicotine in cervical cancer cell lines.

Pub. Date : 2005 Mar

PMID : 15727570






2 Functional Relationships(s)
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1 The VEGF-C levels were significantly increased, while TGF-beta levels were decreased by nicotine in all the cell lines (P < 0.00001). Nicotine transforming growth factor beta 1 Homo sapiens
2 CONCLUSIONS: Nicotine up regulates expression of cell proliferative VEGF-C and EGF-R, while down-regulating anti-proliferative TGF-beta. Nicotine transforming growth factor beta 1 Homo sapiens