Title : The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons.

Pub. Date : 2005 Apr 8

PMID : 15699047






1 Functional Relationships(s)
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1 Additional experiments demonstrated that the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin, which down-regulates Chk1, also sensitized a variety of human carcinoma cell lines to SN-38. tanespimycin checkpoint kinase 1 Homo sapiens