Title : Two functional but noncomplementing Drosophila tyrosine decarboxylase genes: distinct roles for neural tyramine and octopamine in female fertility.

Pub. Date : 2005 Apr 15

PMID : 15691831






3 Functional Relationships(s)
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1 To further clarify the roles of tyramine and its metabolite octopamine, we have cloned two TDC genes from Drosophila melanogaster, dTdc1 and dTdc2. Octopamine Tyrosine decarboxylase 2 Drosophila melanogaster
2 Flies with a mutation in dTdc2 lack neural tyramine and octopamine and are female sterile due to egg retention. Octopamine Tyrosine decarboxylase 2 Drosophila melanogaster
3 The egg retention phenotype of the dTdc2 mutant and the phenotypes associated with ectopic dTdc expression contribute to a model in which octopamine and tyramine have distinct and separable neural activities. Octopamine Tyrosine decarboxylase 2 Drosophila melanogaster