Pub. Date : 2005 Jan
PMID : 15685439
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | TP53 mutations are significantly more frequent in low-grade astrocytomas with promoter methylation of the O(6)-methylguanine-DNA methyltransferase repair gene, suggesting that, in addition to deamination of 5-methylcytosine, exogenous or endogenous alkylation in the O(6) position of guanine may contribute to the formation of these mutations. | Guanine | tumor protein p53 | Homo sapiens |