Title : Epidemiology and etiology of gliomas.

Pub. Date : 2005 Jan

PMID : 15685439






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TP53 mutations are significantly more frequent in low-grade astrocytomas with promoter methylation of the O(6)-methylguanine-DNA methyltransferase repair gene, suggesting that, in addition to deamination of 5-methylcytosine, exogenous or endogenous alkylation in the O(6) position of guanine may contribute to the formation of these mutations. Guanine tumor protein p53 Homo sapiens