Title : Somatic mutations in the neurofibromatosis 1 gene in human tumors.

Pub. Date : 1992 Apr 17

PMID : 1568247






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Since p21ras.GTP is a major regulator of growth and differentiation, mutant neurofibromins resulting from somatic mutations in the NF1 gene might interfere with ras signaling pathways and contribute to the development of tumors. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens