Title : On the control of the hCYP11B2 gene expressing cytochrome P450 aldosterone synthase.

Pub. Date : 2004 Nov

PMID : 15666830






2 Functional Relationships(s)
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1 Here we report that TPA increased the level of phospho-p44/42 MAPK but AII did not. Tetradecanoylphorbol Acetate interferon induced protein 44 Homo sapiens
2 Taken together these results suggest that TPA inhibits the AII-dependent activation of CYP11B2 via the p44/42 MAPK signaling pathway leading to an increase of the level of nuclear JunB. Tetradecanoylphorbol Acetate interferon induced protein 44 Homo sapiens