Pub. Date : 2005 Feb
PMID : 15663890
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Caspase-1 inhibitor Ac-YVAD-CHO attenuates quinolinic acid-induced increases in p53 and apoptosis in rat striatum. | L 709049 | caspase 1 | Rattus norvegicus |
2 | AIM: To study the effects of the caspase-1 inhibitor Ac-YVAD-CHO on quinolinic acid (QA)-induced apoptosis. | L 709049 | caspase 1 | Rattus norvegicus |
3 | Ac-YVAD-CHO inhibited QA-induced increases in caspase-1 activity and p53 protein levels, but had no effect on QA-induced IkappaB-alpha degradation, NF-kappaB or AP-1 activation. | L 709049 | caspase 1 | Rattus norvegicus |