Title : Structural basis for the regulation of insulin-like growth factors by IGF binding proteins.

Pub. Date : 2005 Jan

PMID : 15642270






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Key features of the structures include (1) a disulphide bond ladder that binds to IGF and partially masks the IGF residues responsible for type 1 IGF receptor (IGF-IR) binding, (2) the high-affinity IGF-I interaction site formed by residues 39-82 in a globular fold, and (3) CBP-4 interactions. disulphide insulin like growth factor 1 Homo sapiens