Title : Role of human copper transporter Ctr1 in the transport of platinum-based antitumor agents in cisplatin-sensitive and cisplatin-resistant cells.

Pub. Date : 2004 Dec

PMID : 15634647






1 Functional Relationships(s)
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1 Transfection of expression hemagglutinin-tagged hCtr1 cDNA into SCLC and SR2 cells enhanced the uptake of copper, cisplatin, carboplatin, and oxaliplatin, suggesting that hCtr1 transporter can transport these platinum-based drugs. Oxaliplatin solute carrier family 31 member 1 Homo sapiens