Title : The small-molecule Bcl-2 inhibitor HA14-1 interacts synergistically with flavopiridol to induce mitochondrial injury and apoptosis in human myeloma cells through a free radical-dependent and Jun NH2-terminal kinase-dependent mechanism.

Pub. Date : 2004 Dec

PMID : 15634644






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Combined exposure to flavopiridol and HA14-1 was associated with down-regulation of Mcl-1 and Bcl-xL, Bid cleavage, and mitochondrial translocation of Bax. alvocidib BCL2 like 1 Homo sapiens