Title : [Effects of protein tyrosine kinase, protein tyrosine phosphatase and protein kinase C on the apoptosis of arsenic trioxide treated NB4 cells and human cortex neurons].

Pub. Date : 2004 Oct

PMID : 15634593






3 Functional Relationships(s)
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Protein Name
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1 [Effects of protein tyrosine kinase, protein tyrosine phosphatase and protein kinase C on the apoptosis of arsenic trioxide treated NB4 cells and human cortex neurons]. Arsenic Trioxide EPH receptor A8 Homo sapiens
2 Genistein, a kind of PTK inhibitor, could decrease the increase of [Ca(2+)]i treated by 2, 5, 10 micromol/L As2O3 in a dose-dependent manner. Arsenic Trioxide EPH receptor A8 Homo sapiens
3 CONCLUSIONS: The phosphorylation and dephosphorylation of PTK and PTP participated in nonspecific apoptosis signal transduction pathway related to As2O3, and accompanied with PKC activation. Arsenic Trioxide EPH receptor A8 Homo sapiens