Title : The H2A.Z/H2B dimer is unstable compared to the dimer containing the major H2A isoform.

Pub. Date : 2005 Feb

PMID : 15632282






1 Functional Relationships(s)
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1 To provide insights into how histone variants may impact the thermodynamics of the nucleosome, the stability of the heterodimer between the H2A.Z variant and H2B was determined by urea-induced denaturation, monitored by far-UV circular dichroism, intrinsic Tyr fluorescence intensity, and anisotropy. Tyrosine H2B clustered histone 21 Homo sapiens