Title : The zinc finger Ikaros transcription factor regulates pituitary growth hormone and prolactin gene expression through distinct effects on chromatin accessibility.

Pub. Date : 2005 Apr

PMID : 15618287






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Ikaros selectively deacetylates histone 3 residues on the proximal transfected or endogenous GH promoter and limits access of the Pit1 activator. ikaros POU class 1 homeobox 1 Rattus norvegicus
2 In contrast, Ikaros acetylates histone 3 on the proximal PRL promoter and facilitates Pit1 binding to this region in the same cells. ikaros POU class 1 homeobox 1 Rattus norvegicus