Title : Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goalpha.

Pub. Date : 2005 Mar

PMID : 15618020






10 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goalpha. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
2 Palmitoylation regulates GDP/GTP exchange of G protein by affecting the GTP-binding activity of Goalpha. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
3 The effect of palmitoylation on the GTP-binding activity and conformation of Goalpha protein in hydrophobic and hydrophilic environments was studied. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
4 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
5 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
6 The binding assay was performed with an isotope labeled analog of GTP, GTP-gamma-35S, and its fluorescent analog, BODIPY FL-GTPgammaS was used to detect conformational change in the GTP-binding domain of Goalpha. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
7 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
8 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
9 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens
10 These results imply that palmitoylation may regulate the GTP/GDP exchange of Goalpha by influencing the GTP-binding activity of Goalpha and facilitating the on-off switch function of the G protein in G protein-coupled signal transduction. Guanosine Triphosphate tripartite motif containing 47 Homo sapiens