Title : Effects of histidine-proline-rich glycoprotein on plasminogen activation in solution and on surfaces.

Pub. Date : 2004 Oct

PMID : 15613921






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Here we show that HPRG adsorbed to a glycosaminoglycan (GAG) surface also binds Plg with a Kd value of 0.7 micromol/l. Glycosaminoglycans plasminogen Homo sapiens
2 Here we show that HPRG adsorbed to a glycosaminoglycan (GAG) surface also binds Plg with a Kd value of 0.7 micromol/l. Glycosaminoglycans plasminogen Homo sapiens
3 Specifically, Plg complexed with HPRG on a GAG surface is more readily activated by tissue-type Plg activator than free Plg, with a 10-fold difference in apparent catalytic efficiency (kcat/Km). Glycosaminoglycans plasminogen Homo sapiens
4 Specifically, Plg complexed with HPRG on a GAG surface is more readily activated by tissue-type Plg activator than free Plg, with a 10-fold difference in apparent catalytic efficiency (kcat/Km). Glycosaminoglycans plasminogen Homo sapiens
5 Specifically, Plg complexed with HPRG on a GAG surface is more readily activated by tissue-type Plg activator than free Plg, with a 10-fold difference in apparent catalytic efficiency (kcat/Km). Glycosaminoglycans plasminogen Homo sapiens
6 HPRG also augments the increase in Plg activation caused by fibrinogen fragments either in solution or on GAG surfaces. Glycosaminoglycans plasminogen Homo sapiens