Title : Polyamines modulate carcinogen-induced mutagenesis in vivo.

Pub. Date : 2005

PMID : 15611981






2 Functional Relationships(s)
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1 The increases in mutant frequency were clearly due to ODC transgene activity, since treatment of mice with the ODC inhibitor, alpha-difluoromethylornithine, completely abolished the difference in mutant frequencies between double-transgenic and Big Blue mice. Eflornithine ornithine decarboxylase, structural 1 Mus musculus
2 The increases in mutant frequency were clearly due to ODC transgene activity, since treatment of mice with the ODC inhibitor, alpha-difluoromethylornithine, completely abolished the difference in mutant frequencies between double-transgenic and Big Blue mice. Eflornithine ornithine decarboxylase, structural 1 Mus musculus