Title : Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

Pub. Date : 2005 Jan 6

PMID : 15603755






1 Functional Relationships(s)
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1 CYP2E1 is induced by alcohol and the primary P450 that carries out ethanol oxidation that can lead to the production of activated oxygen species and oxidative stress that elevate ERK1/2 phosphorylation through EGRF/c-Raf signaling. Ethanol mitogen-activated protein kinase 3 Mus musculus