Pub. Date : 1992 Apr
PMID : 1559759
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | For rats reared in the weak cyclic light environment, DMTU (two injections) provided complete protection against rhodopsin loss after intense light exposures of up to 16 hr. | 1,3-dimethylthiourea | rhodopsin | Rattus norvegicus |
| 2 | Only 15% rhodopsin loss was found in cyclic-light DMTU-treated rats after 24 hr of intermittent or continuous light. | 1,3-dimethylthiourea | rhodopsin | Rattus norvegicus |
| 3 | For rats reared in darkness, DMTU treatment resulted in a rhodopsin loss of less than 20% after 8-16 hr of continuous light and approximately 40% after similar exposure to intermittent light. | 1,3-dimethylthiourea | rhodopsin | Rattus norvegicus |
| 4 | Irrespective of the type of light exposure, rhodopsin loss in the dark-reared DMTU-treated rats was nearly identical to that found in uninjected cyclic light-reared animals. | 1,3-dimethylthiourea | rhodopsin | Rattus norvegicus |
| 5 | As measured by rhodopsin levels 2 weeks later, DMTU was most effective when given as two doses administered 24 hr before and just before intense light exposure. | 1,3-dimethylthiourea | rhodopsin | Rattus norvegicus |