Pub. Date : 2005 Jan 21
PMID : 15596148
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we demonstrate that the inducible expression of BCR/ABL in a murine hematopoietic cell line, TonB210, leads to the activation of the Ras family small GTPase Rap1, which is inhibited by the ABL kinase inhibitor imatinib. | Imatinib Mesylate | RAS-related protein 1a | Mus musculus |
| 2 | The Rap1 activity in a CML cell line, K562, was also inhibited by imatinib. | Imatinib Mesylate | RAS-related protein 1a | Mus musculus |