Title : Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway.

Pub. Date : 2005 Feb

PMID : 15574876






3 Functional Relationships(s)
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1 In Saccharomyces cerevisiae, the phosphatidylinositol 4-kinase, Pik1p generates a distinct pool of PtdIns(4)P that is required for normal Golgi structure and secretory function. phosphatidylinositol 4-phosphate 1-phosphatidylinositol 4-kinase Saccharomyces cerevisiae S288C
2 Here, we utilize a synthetic genetic array analysis of a conditional pik1 mutant to identify candidate components of the Pik1p/PtdIns(4)P signaling pathway at the Golgi. phosphatidylinositol 4-phosphate 1-phosphatidylinositol 4-kinase Saccharomyces cerevisiae S288C
3 Here, we utilize a synthetic genetic array analysis of a conditional pik1 mutant to identify candidate components of the Pik1p/PtdIns(4)P signaling pathway at the Golgi. phosphatidylinositol 4-phosphate 1-phosphatidylinositol 4-kinase Saccharomyces cerevisiae S288C