Title : Severe impairment of nucleotide synthesis through inhibition of mitochondrial respiration.

Pub. Date : 2004 Oct

PMID : 15571245






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Since de-novo synthesis of pyrimidine nucleotides is coupled to the mitochondrial respiratory chain (RC) via dehydroorotic acid dehydrogenase (DHODH), respiratory chain dysfunction should impair pyrimidine synthesis. Pyrimidine Nucleotides dihydroorotate dehydrogenase (quinone) Homo sapiens
2 Since de-novo synthesis of pyrimidine nucleotides is coupled to the mitochondrial respiratory chain (RC) via dehydroorotic acid dehydrogenase (DHODH), respiratory chain dysfunction should impair pyrimidine synthesis. Pyrimidine Nucleotides dihydroorotate dehydrogenase (quinone) Homo sapiens