Title : Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model.

Pub. Date : 2004 Nov 15

PMID : 15570007






1 Functional Relationships(s)
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1 Whereas the selective COX-2 inhibitor celecoxib and exisulind, a metabolic product of sulindac, have gained increasing attention as efficacious chemopreventive agents against colon and prostate cancer, not much is known about the underlying molecular targets and mechanisms. Sulindac cytochrome c oxidase II, mitochondrial Mus musculus