Title : Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.

Pub. Date : 2005 Jan

PMID : 15567297






1 Functional Relationships(s)
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1 The activity of the renal peptide transporters PEPT2 and PEPT1 determines-among other factors such as metabolic stability in liver and plasma-the circulatory half-life of penicillins and cephalosporins during therapy. Cephalosporins solute carrier family 15 member 1 Homo sapiens