Title : Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events.

Pub. Date : 2005 Feb

PMID : 15548639






3 Functional Relationships(s)
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1 Polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), are carcinogens suggested to be involved in development of human cancer. Polycyclic Aromatic Hydrocarbons prohibitin 2 Homo sapiens
2 Polycyclic aromatic hydrocarbons (PAHs), such as benzo[a]pyrene (BaP), are carcinogens suggested to be involved in development of human cancer. Polycyclic Aromatic Hydrocarbons prohibitin 2 Homo sapiens
3 In the present study, we found that two PAHs, benz[a]anthracene (BaA) and BaP, can stimulate proliferation of human breast carcinoma MCF-7 cells at concentrations 100 nM and higher. Polycyclic Aromatic Hydrocarbons prohibitin 2 Homo sapiens