Title : Phospholipase d signaling and extracellular signal-regulated kinase-1 and -2 phosphorylation (activation) are required for maximal phorbol ester-induced transglutaminase activity, a marker of keratinocyte differentiation.

Pub. Date : 2005 Mar

PMID : 15537826






1 Functional Relationships(s)
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1 However, inhibition of PLD-mediated signal generation had only a small effect on TPA-elicited ERK-1/2 phosphorylation (activation), whereas inhibition of ERK-1/2 did not affect PLD activation, suggesting that these two pathways likely operate largely in parallel. Tetradecanoylphorbol Acetate mitogen-activated protein kinase 3 Mus musculus