Title : ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression.

Pub. Date : 2004 Dec 10

PMID : 15530425






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Ramiprilat dose-dependently suppressed AngII-induced upregulation of IL-8 and MCP-1. ramiprilat C-X-C motif chemokine ligand 8 Homo sapiens
2 In addition, ramiprilat downregulated NF-kappaB activity and thereby reduced the AngII-induced release of IL-8 and MCP-1 in monocytes. ramiprilat C-X-C motif chemokine ligand 8 Homo sapiens