Title : Aberrant [correction of Abberant] cytosolic calcium ion mobilization in chronic granulomatous disease neutrophils.

Pub. Date : 2004 Jun

PMID : 15527168






1 Functional Relationships(s)
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1 We observed that PMN from a female CGD carrier, with a discrete mutation in one allele of the pg91(phox) gene and exhibiting extreme lyonization, showed a consistently and remarkably delayed PMN cytosolic calcium response to the tripeptide fMLP or leukotriene B4 (LTB4). Leukotrienes formyl peptide receptor 1 Homo sapiens