Title : Methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineurin/Crz1-mediated pathway in Saccharomyces cerevisiae.

Pub. Date : 2005 Jan 7

PMID : 15520007






1 Functional Relationships(s)
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1 We have previously reported that expression of GLO1, coding for the major enzyme detoxifying MG, was induced by osmotic stress in a high osmolarity glycerol (HOG)-mitogen-activated protein (MAP) kinase-dependent manner in Saccharomyces cerevisiae. Glycerol lactoylglutathione lyase GLO1 Saccharomyces cerevisiae S288C