Title : Carbonic anhydrase inhibitors: inhibition of the membrane-bound human isozyme IV with anions.

Pub. Date : 2004 Dec 6

PMID : 15501038






1 Functional Relationships(s)
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1 Excellent hCA IV inhibitory properties showed sulfamic acid, sulfamide, phenylboronic acid and phenylarsonic acid, with K(i)"s in the range of 0.87-0.93 microM, whereas their affinities for the other investigated isozymes were in the millimolar range. sulfamic acid carbonic anhydrase 4 Homo sapiens