Title : Human polynucleotide phosphorylase (hPNPaseold-35): a potential link between aging and inflammation.

Pub. Date : 2004 Oct 15

PMID : 15492272






2 Functional Relationships(s)
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Protein Name
Organism
1 The generation of ROS and activation of NF-kappaB by hPNPase(old-35) are prevented by treatment with a cell-permeable antioxidant, N-acetyl-l-cysteine. Acetylcysteine polyribonucleotide nucleotidyltransferase 1 Homo sapiens
2 Infection with Ad.hPNPase(old-35) enhances the production of interleukin (IL)-6 and IL-8, two classical NF-kappaB-responsive cytokines, and this induction is inhibited by N-acetyl-l-cysteine. Acetylcysteine polyribonucleotide nucleotidyltransferase 1 Homo sapiens