Title : Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo.

Pub. Date : 2004 Oct 15

PMID : 15492235






1 Functional Relationships(s)
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1 Treatment of established neuroblastoma xenografts in nude rats with the dual COX-1/COX-2 inhibitor diclofenac or the COX-2-specific inhibitor celecoxib significantly inhibited tumor growth in vivo (P < 0.001). Diclofenac cytochrome c oxidase II, mitochondrial Rattus norvegicus