Title : COOH-terminal 26-amino acid residues of progastrin are sufficient for stimulation of mitosis in murine colonic epithelium in vivo.

Pub. Date : 2005 Mar

PMID : 15486344






1 Functional Relationships(s)
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1 Transgenic mice (hGAS) that overexpress human progastrin are more susceptible than wild-type mice (FVB/N) to the induction of colonic aberrant crypt foci (ACF) and adenomas by the chemical carcinogen azoxymethane. Azoxymethane gastrin Homo sapiens