Title : Characterization of afloqualone N-glucuronidation: species differences and identification of human UDP-glucuronosyltransferase isoform(s).

Pub. Date : 2005 Jan

PMID : 15475412






2 Functional Relationships(s)
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1 In contrast, the K(m) value of AFQ N-glucuronidation in recombinant UGT1A3 microsomes was relatively close to that in human jejunum microsomes. Nitrogen UDP glucuronosyltransferase family 1 member A3 Homo sapiens
2 These results demonstrate that AFQ N-glucuronidation in human is mainly catalyzed by UGT1A4 in the liver and by UGT1A3, as well as UGT1A4 in the intestine. Nitrogen UDP glucuronosyltransferase family 1 member A3 Homo sapiens