Pub. Date : 2005 Feb
PMID : 15470230
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Different acceptor specificities of two glucuronyltransferases involved in the biosynthesis of HNK-1 carbohydrate. | Carbohydrates | beta-1,3-glucuronyltransferase 1 | Homo sapiens |
| 2 | The biosynthesis of HNK-1 carbohydrate is mainly regulated by two glucuronyltransferases (GlcAT-P and GlcAT-S) and a sulfotransferase (HNK-1 ST). | Carbohydrates | beta-1,3-glucuronyltransferase 1 | Homo sapiens |
| 3 | To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes. | Carbohydrates | beta-1,3-glucuronyltransferase 1 | Homo sapiens |
| 4 | To determine how the two glucuronyltransferases are involved in the biosynthesis of the HNK-1 carbohydrate, we prepared soluble forms of GlcAT-P and GlcAT-S fused with the IgG-binding domain of protein A and then compared the enzymatic properties of the two enzymes. | Carbohydrates | beta-1,3-glucuronyltransferase 1 | Homo sapiens |
| 5 | These lines of evidence indicate that these two enzymes have significantly different acceptor specificities, suggesting that they may synthesize functionally and structurally different HNK-1 carbohydrates in the nervous system. | Carbohydrates | beta-1,3-glucuronyltransferase 1 | Homo sapiens |