Title : The vaccinia virus B1R kinase induces p53 downregulation by an Mdm2-dependent mechanism.

Pub. Date : 2004 Oct 25

PMID : 15464845






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The over-expressed B1R protein induces the degradation of p53 in a concentration-dependent manner and is lost when Ser15 and Th18 are changed to alanine or when the B1R kinase is inactivated by introducing the K149Q substitution. Alanine tumor protein p53 Homo sapiens