Title : Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway.

Pub. Date : 2004 Dec 3

PMID : 15459192






5 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway. Phytic Acid nucleoporin GLE1 Saccharomyces cerevisiae S288C
2 Production of inositol hexakisphosphate (IP6) by Ipk1, the inositol-1,3,4,5,6-pentakisphosphate 2-kinase, is required for Gle1-mediated mRNA export in Saccharomyces cerevisiae cells. Phytic Acid nucleoporin GLE1 Saccharomyces cerevisiae S288C
3 Production of inositol hexakisphosphate (IP6) by Ipk1, the inositol-1,3,4,5,6-pentakisphosphate 2-kinase, is required for Gle1-mediated mRNA export in Saccharomyces cerevisiae cells. Phytic Acid nucleoporin GLE1 Saccharomyces cerevisiae S288C
4 Additionally, the cytoplasmic production of IP6 by plasma membrane-anchored Ipk1 rescued a gle1-2 ipk1-4 synthetic lethal mutant. Phytic Acid nucleoporin GLE1 Saccharomyces cerevisiae S288C
5 Thus, cytoplasmic IP6 production is sufficient for mediating the Gle1-mRNA export pathway. Phytic Acid nucleoporin GLE1 Saccharomyces cerevisiae S288C