Title : The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings.

Pub. Date : 2004 Dec

PMID : 15458611






3 Functional Relationships(s)
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1 The aim of this study is to investigate a possible association between this 5-HT1A receptor variant and antidepressant response to fluvoxamine in a sample of 262 mood-disorder subjects (151 major depressed and 111 bipolars) treated with fluvoxamine for 6 wk. Fluvoxamine 5-hydroxytryptamine receptor 1A Homo sapiens
2 The aim of this study is to investigate a possible association between this 5-HT1A receptor variant and antidepressant response to fluvoxamine in a sample of 262 mood-disorder subjects (151 major depressed and 111 bipolars) treated with fluvoxamine for 6 wk. Fluvoxamine 5-hydroxytryptamine receptor 1A Homo sapiens
3 In bipolars, 5-HT1A*C/C genotype carriers showed a better response to fluvoxamine (p=0.036), independently from clinical variables. Fluvoxamine 5-hydroxytryptamine receptor 1A Homo sapiens